Geroscience: A Translational Review

Research Summary

A translational review of geroscience — the field that studies how ageing-related biological pathways can be modified to delay disease and disability.

Who Or What Was Studied?

A review of existing research rather than a new study. It covers disease-focused treatments, candidate geroscience interventions, animal models and the human evidence available for each.

What Did The Research Show?

• Disease-focused treatments such as statins do not substantially change ageing’s contribution to disease and decline.
• In animal models several interventions do alter ageing itself.
• The review separates which of these have meaningful human evidence from those that remain preclinical.

Limitations And Interpretation

• It is a review, not a trial: it does not establish that any single intervention slows human ageing.
• No treatment recommendation is offered.