1. mTOR Pathway and Aging The mTOR pathway controls cell growth, protein synthesis, and metabolism and plays a critical role in muscle health. As we age, overactive mTOR signaling contributes to problems like muscle wasting (sarcopenia), chronic inflammation, and mitochondrial decline—key challenges associated with rapamycin for aging muscles. This process aligns with broader insights into…

Introduction Dr. Joan Mannick is a medical doctor who has dedicated her career to studying how the body ages. She grew up in a family of doctors and later moved from clinical medicine into research, focusing on ways to help people stay healthier as they grow older. Her work centers on a key biological pathway…