Can a drug originally used in organ transplant medicine hold the key to preventing Alzheimer’s disease? As we move into 2025, Rapamycin has transitioned from a niche "longevity molecule" to a primary subject of intense clinical investigation for dementia. Rapamycin is an FDA-approved mTOR inhibitor that researchers believe may slow the biological processes of aging…

For decades, people living with ME/CFS (Myalgic Encephalomyelitis / Chronic Fatigue Syndrome) have waited for treatments that address more than just symptoms. Now, new research led by Dr. Avik Roy at the Simmaron Research Institute suggests that an unexpected molecule—rapamycin—might help restore the underlying biology that drives fatigue in many patients. Why Rapamycin? A Closer…

Emerging evidence suggests that Rapamycin — an mTOR inhibitor long used in clinical settings — may suppress core aging mechanisms by moderating cellular hyperfunction, delaying age-related diseases, and extending lifespan across species. This positions Rapamycin and its analogs as serious candidates for “anti-aging” interventions in humans. Background: Why mTOR and Cellular Hyperfunction Matter in Aging…

“New research suggests low-dose rapamycin may reduce DNA damage in aging immune cells, supporting healthier aging and potentially extending human healthspan.” Recent findings suggest that rapamycin, an mTOR-inhibiting compound with established geroprotective effects in animal models, may enhance DNA damage resilience in aging human immune cells. This mechanism provides a compelling biologic rationale for its…

From longevity communities to advanced clinical research, rapamycin is emerging as one of the most promising tools for supporting healthy aging in women. Today, both scientific discoveries and real-world experiences are shaping a hopeful new chapter in women’s health and longevity. A Growing Movement: Women Turning to Rapamycin What excites me most is not only…

Inspired by a Nature Communications study led by Dr. Ronald Desrosiers, University of Miami Miller School of Medicine. Beyond Longevity: Rapamycin Steps Into the Future of Immunotherapy Known for its potential to extend lifespan and improve metabolic health, rapamycin continues to surprise the scientific world with its versatility.Now, researchers have uncovered another powerful application —…

Based on Dr. Mikhail V. Blagosklonny’s paper published in Aging (Albany NY), 2023. Does Aging Really Exist — or Just Age-Related Diseases? In his thought-provoking 2023 paper, Dr. Mikhail V. Blagosklonny of Roswell Park Comprehensive Cancer Center challenges one of biology’s most fundamental questions: does aging exist as an independent process, or is it merely…

Introduction How rapamycin could help dogs and cats live longer, healthier lives? The science of pet longevity is entering a new era.For an overview of rapamycin’s broader impact on aging, you can also explore Rapamycin and Longevity Science. Originally discovered on Easter Island in the 1970s, this compound was first developed as an immunosuppressant for…

The Scientific Picture of Healthy Aging With Rapamycin “The scientific picture is still evolving, but what we see now marks an exciting beginning in understanding rapamycin’s impact on human health and longevity.”For a broader overview of how rapamycin fits into modern longevity science, you can see Rapamycin and Longevity Science. New Research Highlights the Expanding…

From brain health to personalized medicine, new studies are expanding how rapamycin could shape the next era of longevity science. Here’s what researchers are exploring next. Beyond What We Already Know For years, rapamycin has been the molecule everyone talks about in longevity science — but what comes next might be even more exciting.The first…